He was born in the village of Frangiades in Zagori and from Bucharest where he was studying he returned to Greece in 1821 to take an active part in the Struggle. He was the secretary of the hero of the Revolution Archimandrite Grigorio Papaflessas. His surname was Karagiannopoulos, but he replaced it with the pseudonym Tissamenos by which he is known in all the texts of the Agon. During the period of Governor I. Kapodistrias, he served in the General Secretariat of the Territory as an associate of Secretary Spy. Trikoupi in administrative matters. During the reign of Otto he initially served in administrative positions and was Minister of Finance: a) from 4/10/1839 to 24/1/1841 in the Government of King Otto, b) from 24/1/1841 to 10/8/ 1841 in the Government Alex. Mavrokordatos and c) from 10/8/1841 to 9/11/1842 in the Government of King Otto. He was then appointed Vice-President of the Court of Auditors (Government Gazette 39) and then by promotion he was President of the Court of Auditors from 10/11/1842 (Government Gazette 28) until 20/10/1843. During the movement of 1854 in Thessaly, Epirus and Macedonia he organized a corps of volunteers who operated in Epirus and fought at Peta Artas. After the failure of the movement, he retired from active politics and served for the second time as President of the Auditing Court from 6/5/1865 to 2/7/1866. He died on 23/7/1872.